University of California San Francisco

Linda Ferrell - 144
Linda
Ferrell
MD

Emeritus Professor
Departments of Pathology & Laboratory Medicine 

Address

513 Parnassus Avenue, MSB, #001
San Francisco, CA 94143
United States

Email: [email protected]
Phone: 415-353-1090
Fax: 415-353-1200

    Biography

    Linda Ferrell, M.D. is a liver pathologist, Professor of Pathology, Vice Chair of Clinical Services, and Director of Surgical Pathology at UCSF. She specializes in the diagnosis of liver disorders such as: benign liver tumors, cirrhosis, hepatitis B, hepatitis C, hepatocellular carcinoma, vascular lesions, metastastic cancer to the liver, liver transplantation, nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). She graduated summa cum laude from the University of Kansas, where she also attended medical school and completed her residency. Dr. Ferrell went on to complete her surgical pathology fellowship at the University of California, San Francisco, while concurrently serving as Chief Resident. She has been the recipient of numerous awards, published a large number of articles and book chapters and currently serves as a co-editor on two medical textbooks in her field of expertise. In early 2010 she was elected Vice President of the United States and Canadian Academy of Pathology (USCAP). Information pertaining to her awards and published materials can be found on her Curriculum Vitae.

    Education

    Institution Degree Dept or School End Date
    University of Kansas M.D. School of Medicine 1977

    Board Certifications

    • American Board of Pathology, Anatomic Pathology

    Clinical Expertise

    Benign Liver Tumors
    Cirrhosis
    Hepatitis B
    Hepatitis C
    Hepatocellular Carcinoma (Liver Cancer)
    Liver Metastases
    Liver Transplantation
    Nonalcoholic Fatty Liver Disease

    Program Affiliations

    Member, UCSF Helen Diller Family Comprehensive Cancer Center
    UCSF Medical Center Organ Transplant Program

    Research Narrative

    Dr. Ferrell's research interests are primarily liver pathology, with emphasis on liver transplantation, fatty liver, hepatitis B and C and liver tumors, particularly well-differentiated hepatocellular tumors and vascular lesions. She actively participated in the World Congress' Consensus Groups for the nomenclature of nodules in the liver and recommendations for terminology for hepatic allograft rejection. Dr. Ferrell's studies on liver pathology in recurrent hepatitis C after transplantation and on the diagnosis of dysplastic nodules have been recognized internationally as leading papers ion these topics. She was also involved in a recent evaluation and review of benign liver tumors in coordination with the International Liver Pathology Study Group and the Laennec Society. Her current ongoing studies involve unusual variants of tumors (HCC, vascular, others), vascular malformations in the liver and other markers in well-differentiated hepatocellular tumors.

    Research Interests

    • Liver pathology, emphasizing liver transplantation
    • Fatty liver
    • Hepatitis B and C
    • Liver tumors
    • Well-differentiated hepatocellular tumors & vascular lesions

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 235
    1. Well-differentiated hepatocellular neoplasm of uncertain malignant potential.
      Balabaud C, Bioulac-Sage P, Ferrell L, Kakar S, Paradis V, Quaglia A, Sempoux C, Thung S, Zucman-Rossi J| | PubMed
    2. Segmental cholangiectasia clinically worrisome for cholangiocarcinoma: comparison with recurrent pyogenic cholangitis.
      Zhao L, Hosseini M, Wilcox R, Liu Q, Crook T, Taxy JB, Ferrell L, Hart J| | PubMed
    3. Monoclonal light chain deposits within the stomach manifesting as immunotactoid gastropathy.
      Jen KY, Fix OK, Foster EN, Laszik ZG, Ferrell LD| | PubMed
    4. Hepatocellular carcinoma arising in adenoma: similar immunohistochemical and cytogenetic features in adenoma and hepatocellular carcinoma portions of the tumor.
      Kakar S, Grenert JP, Paradis V, Pote N, Jakate S, Ferrell LD| | PubMed
    5. Aberrant centrizonal features in chronic hepatic venous outflow obstruction: centrilobular mimicry of portal-based disease.
      Krings G, Can B, Ferrell L| | PubMed
    6. Hepatocellular adenomas in a large community population, 2000 to 2010: reclassification per current World Health Organization classification and results of long-term follow-up.
      Shafizadeh N, Genrich G, Ferrell L, Kakar S| | PubMed
    7. Different collagen types show distinct rates of increase from early to late stages of hepatitis C-related liver fibrosis.
      Chen W, Rock JB, Yearsley MM, Ferrell LD, Frankel WL| | PubMed
    8. Well-differentiated hepatocellular neoplasm of uncertain malignant potential: proposal for a new diagnostic category--reply.
      Kakar S, Evason KJ, Ferrell LD| | PubMed
    9. Diagnostic utility and limitations of glutamine synthetase and serum amyloid-associated protein immunohistochemistry in the distinction of focal nodular hyperplasia and inflammatory hepatocellular adenoma.
      Joseph NM, Ferrell LD, Jain D, Torbenson MS, Wu TT, Yeh MM, Kakar S| | PubMed
    10. Focal Nodular Hyperplasia and Hepatocellular Adenoma around the World Viewed through the Scope of the Immunopathological Classification.
      Balabaud C, Al-Rabih WR, Chen PJ, Evason K, Ferrell L, Hernandez-Prera JC, Huang SF, Longerich T, Park YN, Quaglia A, Schirmacher P, Sempoux C, Thung SN, Torbenson M, Wee A, Yeh MM, Yeh SH, Le Bail B, Zucman-Rossi J, Bioulac-Sage P| | PubMed