University of California San Francisco

Linda Ferrell - 144
Linda
Ferrell
MD

Emeritus Professor
Departments of Pathology & Laboratory Medicine 

Address

513 Parnassus Avenue, MSB, #001
San Francisco, CA 94143
United States

Email: [email protected]
Phone: 415-353-1090
Fax: 415-353-1200

    Biography

    Linda Ferrell, M.D. is a liver pathologist, Professor of Pathology, Vice Chair of Clinical Services, and Director of Surgical Pathology at UCSF. She specializes in the diagnosis of liver disorders such as: benign liver tumors, cirrhosis, hepatitis B, hepatitis C, hepatocellular carcinoma, vascular lesions, metastastic cancer to the liver, liver transplantation, nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). She graduated summa cum laude from the University of Kansas, where she also attended medical school and completed her residency. Dr. Ferrell went on to complete her surgical pathology fellowship at the University of California, San Francisco, while concurrently serving as Chief Resident. She has been the recipient of numerous awards, published a large number of articles and book chapters and currently serves as a co-editor on two medical textbooks in her field of expertise. In early 2010 she was elected Vice President of the United States and Canadian Academy of Pathology (USCAP). Information pertaining to her awards and published materials can be found on her Curriculum Vitae.

    Education

    Institution Degree Dept or School End Date
    University of Kansas M.D. School of Medicine 1977

    Board Certifications

    • American Board of Pathology, Anatomic Pathology

    Clinical Expertise

    Benign Liver Tumors
    Cirrhosis
    Hepatitis B
    Hepatitis C
    Hepatocellular Carcinoma (Liver Cancer)
    Liver Metastases
    Liver Transplantation
    Nonalcoholic Fatty Liver Disease

    Program Affiliations

    Member, UCSF Helen Diller Family Comprehensive Cancer Center
    UCSF Medical Center Organ Transplant Program

    Research Narrative

    Dr. Ferrell's research interests are primarily liver pathology, with emphasis on liver transplantation, fatty liver, hepatitis B and C and liver tumors, particularly well-differentiated hepatocellular tumors and vascular lesions. She actively participated in the World Congress' Consensus Groups for the nomenclature of nodules in the liver and recommendations for terminology for hepatic allograft rejection. Dr. Ferrell's studies on liver pathology in recurrent hepatitis C after transplantation and on the diagnosis of dysplastic nodules have been recognized internationally as leading papers ion these topics. She was also involved in a recent evaluation and review of benign liver tumors in coordination with the International Liver Pathology Study Group and the Laennec Society. Her current ongoing studies involve unusual variants of tumors (HCC, vascular, others), vascular malformations in the liver and other markers in well-differentiated hepatocellular tumors.

    Research Interests

    • Liver pathology, emphasizing liver transplantation
    • Fatty liver
    • Hepatitis B and C
    • Liver tumors
    • Well-differentiated hepatocellular tumors & vascular lesions

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 235
    1. Imaging prediction of residual hepatocellular carcinoma after locoregional therapy in patients undergoing liver transplantation or partial hepatectomy.
      Ehman EC, Umetsu SE, Ohliger MA, Fidelman N, Ferrell LD, Yeh BM, Yee J, Hope TA| | PubMed
    2. Endothelial notch signaling is essential to prevent hepatic vascular malformations in mice.
      Cuervo H, Nielsen CM, Simonetto DA, Ferrell L, Shah VH, Wang RA| | PubMed
    3. Proliferative index facilitates distinction between benign biliary lesions and intrahepatic cholangiocarcinoma.
      Tsokos CG, Krings G, Yilmaz F, Ferrell LD, Gill RM| | PubMed
    4. Rate of observation and inter-observer agreement for LI-RADS major features at CT and MRI in 184 pathology proven hepatocellular carcinomas.
      Ehman EC, Behr SC, Umetsu SE, Fidelman N, Yeh BM, Ferrell LD, Hope TA| | PubMed
    5. Role of aetiology in the progression, regression, and parenchymal remodelling of liver disease: implications for liver biopsy interpretation.
      Quaglia A, Alves VA, Balabaud C, Bhathal PS, Bioulac-Sage P, Crawford JM, Dhillon AP, Ferrell L, Guido M, Hytiroglou P, Nakanuma Y, Paradis V, Snover DC, Theise ND, Thung SN, Tsui WM, van Leeuwen DJ, International Liver Pathology Study Group| | PubMed
    6. Hepatic small vessel neoplasm, a rare infiltrative vascular neoplasm of uncertain malignant potential.
      Gill RM, Buelow B, Mather C, Joseph NM, Alves V, Brunt EM, Liu TC, Makhlouf H, Marginean C, Nalbantoglu I, Sempoux C, Snover DC, Thung SN, Yeh MM, Ferrell LD| | PubMed
    7. Acidophil bodies in nonalcoholic steatohepatitis.
      Yeh MM, Belt P, Brunt EM, Kowdley KV, Wilson LA, Ferrell L, Nonalcoholic Steatohepatitis Clinical Research Network| | PubMed
    8. Expression of liver fatty acid binding protein in hepatocellular carcinoma.
      Cho SJ, Ferrell LD, Gill RM| | PubMed
    9. Hepatocellular Carcinoma Arising in an HNF-1α-Mutated Adenoma in a 23-Year-Old Woman with Maturity-Onset Diabetes of the Young: A Case Report.
      Stueck AE, Qu Z, Huang MA, Campreciós G, Ferrell LD, Thung SN| | PubMed
    10. Immunohistochemical pitfalls in the diagnosis of hepatocellular adenomas and focal nodular hyperplasia: accurate understanding of diverse staining patterns is essential for diagnosis and risk assessment.
      Kakar S, Torbenson M, Jain D, Wu TT, Yeh M, Ferrell LD| | PubMed