University of California San Francisco

Linda Ferrell - 144
Linda
Ferrell
MD

Emeritus Professor
Departments of Pathology & Laboratory Medicine 

Address

513 Parnassus Avenue, MSB, #001
San Francisco, CA 94143
United States

Email: [email protected]
Phone: 415-353-1090
Fax: 415-353-1200

    Biography

    Linda Ferrell, M.D. is a liver pathologist, Professor of Pathology, Vice Chair of Clinical Services, and Director of Surgical Pathology at UCSF. She specializes in the diagnosis of liver disorders such as: benign liver tumors, cirrhosis, hepatitis B, hepatitis C, hepatocellular carcinoma, vascular lesions, metastastic cancer to the liver, liver transplantation, nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). She graduated summa cum laude from the University of Kansas, where she also attended medical school and completed her residency. Dr. Ferrell went on to complete her surgical pathology fellowship at the University of California, San Francisco, while concurrently serving as Chief Resident. She has been the recipient of numerous awards, published a large number of articles and book chapters and currently serves as a co-editor on two medical textbooks in her field of expertise. In early 2010 she was elected Vice President of the United States and Canadian Academy of Pathology (USCAP). Information pertaining to her awards and published materials can be found on her Curriculum Vitae.

    Education

    Institution Degree Dept or School End Date
    University of Kansas M.D. School of Medicine 1977

    Board Certifications

    • American Board of Pathology, Anatomic Pathology

    Clinical Expertise

    Benign Liver Tumors
    Cirrhosis
    Hepatitis B
    Hepatitis C
    Hepatocellular Carcinoma (Liver Cancer)
    Liver Metastases
    Liver Transplantation
    Nonalcoholic Fatty Liver Disease

    Program Affiliations

    Member, UCSF Helen Diller Family Comprehensive Cancer Center
    UCSF Medical Center Organ Transplant Program

    Research Narrative

    Dr. Ferrell's research interests are primarily liver pathology, with emphasis on liver transplantation, fatty liver, hepatitis B and C and liver tumors, particularly well-differentiated hepatocellular tumors and vascular lesions. She actively participated in the World Congress' Consensus Groups for the nomenclature of nodules in the liver and recommendations for terminology for hepatic allograft rejection. Dr. Ferrell's studies on liver pathology in recurrent hepatitis C after transplantation and on the diagnosis of dysplastic nodules have been recognized internationally as leading papers ion these topics. She was also involved in a recent evaluation and review of benign liver tumors in coordination with the International Liver Pathology Study Group and the Laennec Society. Her current ongoing studies involve unusual variants of tumors (HCC, vascular, others), vascular malformations in the liver and other markers in well-differentiated hepatocellular tumors.

    Research Interests

    • Liver pathology, emphasizing liver transplantation
    • Fatty liver
    • Hepatitis B and C
    • Liver tumors
    • Well-differentiated hepatocellular tumors & vascular lesions

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 235
    1. Hepatic steatosis estimated microscopically versus digital image analysis.
      Hall AR, Dhillon AP, Green AC, Ferrell L, Crawford JM, Alves V, Balabaud C, Bhathal P, Bioulac-Sage P, Guido M, Hytiroglou P, Nakanuma Y, Paradis V, Quaglia A, Snover D, Theise N, Thung S, Tsui W, van Leeuwen DJ| | PubMed
    2. Clinicopathologic characteristics and survival outcomes of patients with fibrolamellar carcinoma: data from the fibrolamellar carcinoma consortium.
      Ang CS, Kelley RK, Choti MA, Cosgrove DP, Chou JF, Klimstra D, Torbenson MS, Ferrell L, Pawlik TM, Fong Y, O'Reilly EM, Ma J, McGuire J, Vallarapu GP, Griffin A, Stipa F, Capanu M, Dematteo RP, Venook AP, Abou-Alfa GK| | PubMed
    3. Atypical hepatocellular adenoma-like neoplasms with β-catenin activation show cytogenetic alterations similar to well-differentiated hepatocellular carcinomas.
      Evason KJ, Grenert JP, Ferrell LD, Kakar S| | PubMed
    4. Liver steatosis: concordance of MR imaging and MR spectroscopic data with histologic grade.
      Noworolski SM, Lam MM, Merriman RB, Ferrell L, Qayyum A| | PubMed
    5. Outcomes of liver transplant recipients with hepatitis C and human immunodeficiency virus coinfection.
      Terrault NA, Roland ME, Schiano T, Dove L, Wong MT, Poordad F, Ragni MV, Barin B, Simon D, Olthoff KM, Johnson L, Stosor V, Jayaweera D, Fung J, Sherman KE, Subramanian A, Millis JM, Slakey D, Berg CL, Carlson L, Ferrell L, Stablein DM, Odim J, Fox L, Stock PG, Solid Organ Transplantation in HIV: Multi-Site Study Investigators| | PubMed
    6. Ethnicity and nonalcoholic fatty liver disease.
      Bambha K, Belt P, Abraham M, Wilson LA, Pabst M, Ferrell L, Unalp-Arida A, Bass N, Nonalcoholic Steatohepatitis Clinical Research Network Research Group| | PubMed
    7. Solitary rectal ulcer syndrome in children and adolescents.
      Perito ER, Mileti E, Dalal DH, Cho SJ, Ferrell LD, McCracken M, Heyman MB| | PubMed
    8. Beyond "cirrhosis": a proposal from the International Liver Pathology Study Group.
      Hytiroglou P, Snover DC, Alves V, Balabaud C, Bhathal PS, Bioulac-Sage P, Crawford JM, Dhillon AP, Ferrell L, Guido M, Nakanuma Y, Paradis V, Quaglia A, Theise ND, Thung SN, Tsui WM, van Leeuwen DJ| | PubMed
    9. Hepatic steatosis at 1 year is an additional predictor of subsequent fibrosis severity in liver transplant recipients with recurrent hepatitis C virus.
      Brandman D, Pingitore A, Lai JC, Roberts JP, Ferrell L, Bass NM, Terrault NA| | PubMed
    10. Costaining for keratins 8/18 plus ubiquitin improves detection of hepatocyte injury in nonalcoholic fatty liver disease.
      Guy CD, Suzuki A, Burchette JL, Brunt EM, Abdelmalek MF, Cardona D, McCall SJ, Ünalp A, Belt P, Ferrell LD, Diehl AM, Nonalcoholic Steatohepatitis Clinical Research Network| | PubMed