University of California San Francisco

Linda Ferrell - 144
Linda
Ferrell
MD

Emeritus Professor
Departments of Pathology & Laboratory Medicine 

Address

513 Parnassus Avenue, MSB, #001
San Francisco, CA 94143
United States

Email: [email protected]
Phone: 415-353-1090
Fax: 415-353-1200

    Biography

    Linda Ferrell, M.D. is a liver pathologist, Professor of Pathology, Vice Chair of Clinical Services, and Director of Surgical Pathology at UCSF. She specializes in the diagnosis of liver disorders such as: benign liver tumors, cirrhosis, hepatitis B, hepatitis C, hepatocellular carcinoma, vascular lesions, metastastic cancer to the liver, liver transplantation, nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). She graduated summa cum laude from the University of Kansas, where she also attended medical school and completed her residency. Dr. Ferrell went on to complete her surgical pathology fellowship at the University of California, San Francisco, while concurrently serving as Chief Resident. She has been the recipient of numerous awards, published a large number of articles and book chapters and currently serves as a co-editor on two medical textbooks in her field of expertise. In early 2010 she was elected Vice President of the United States and Canadian Academy of Pathology (USCAP). Information pertaining to her awards and published materials can be found on her Curriculum Vitae.

    Education

    Institution Degree Dept or School End Date
    University of Kansas M.D. School of Medicine 1977

    Board Certifications

    • American Board of Pathology, Anatomic Pathology

    Clinical Expertise

    Benign Liver Tumors
    Cirrhosis
    Hepatitis B
    Hepatitis C
    Hepatocellular Carcinoma (Liver Cancer)
    Liver Metastases
    Liver Transplantation
    Nonalcoholic Fatty Liver Disease

    Program Affiliations

    Member, UCSF Helen Diller Family Comprehensive Cancer Center
    UCSF Medical Center Organ Transplant Program

    Research Narrative

    Dr. Ferrell's research interests are primarily liver pathology, with emphasis on liver transplantation, fatty liver, hepatitis B and C and liver tumors, particularly well-differentiated hepatocellular tumors and vascular lesions. She actively participated in the World Congress' Consensus Groups for the nomenclature of nodules in the liver and recommendations for terminology for hepatic allograft rejection. Dr. Ferrell's studies on liver pathology in recurrent hepatitis C after transplantation and on the diagnosis of dysplastic nodules have been recognized internationally as leading papers ion these topics. She was also involved in a recent evaluation and review of benign liver tumors in coordination with the International Liver Pathology Study Group and the Laennec Society. Her current ongoing studies involve unusual variants of tumors (HCC, vascular, others), vascular malformations in the liver and other markers in well-differentiated hepatocellular tumors.

    Research Interests

    • Liver pathology, emphasizing liver transplantation
    • Fatty liver
    • Hepatitis B and C
    • Liver tumors
    • Well-differentiated hepatocellular tumors & vascular lesions

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 235
    1. An early lesion in hepatic carcinogenesis: loss of heterozygosity in human cirrhotic livers and dysplastic nodules at the 1p36-p34 region.
      Sun M, Eshleman JR, Ferrell LD, Jacobs G, Sudilovsky EC, Tuthill R, Hussein MR, Sudilovsky O| | PubMed
    2. Clinical course and biochemistry of sialuria.
      Enns GM, Seppala R, Musci TJ, Weisiger K, Ferrell LD, Wenger DA, Gahl WA, Packman S| | PubMed
    3. Liver transplantation for hepatocellular carcinoma: expansion of the tumor size limits does not adversely impact survival.
      Yao FY, Ferrell L, Bass NM, Watson JJ, Bacchetti P, Venook A, Ascher NL, Roberts JP| | PubMed
    4. Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice.
      Wang R, Ferrell LD, Faouzi S, Maher JJ, Bishop JM| | PubMed
    5. SCVIR annual meeting film panel session: diagnosis and discussion of case 5.
      Kerlan RK, LaBerge JM, Bass NM, Ferrell LD, Wilson MW, Gordon RL| | PubMed
    6. Altered distribution of beta-catenin, and its binding proteins E-cadherin and APC, in ulcerative colitis-related colorectal cancers.
      Aust DE, Terdiman JP, Willenbucher RF, Chew K, Ferrell L, Florendo C, Molinaro-Clark A, Baretton GB, Löhrs U, Waldman FM| | PubMed
    7. Severity of iron overload in patients with sickle cell disease receiving chronic red blood cell transfusion therapy.
      Harmatz P, Butensky E, Quirolo K, Williams R, Ferrell L, Moyer T, Golden D, Neumayr L, Vichinsky E| | PubMed
    8. Liver pathology: cirrhosis, hepatitis, and primary liver tumors. Update and diagnostic problems.
      Ferrell L| | PubMed
    9. HCV-related fibrosis progression following liver transplantation: increase in recent years.
      Berenguer M, Ferrell L, Watson J, Prieto M, Kim M, Rayón M, Córdoba J, Herola A, Ascher N, Mir J, Berenguer J, Wright TL| | PubMed
    10. Utility of CD34 reactivity in evaluating focal nodular hepatocellular lesions sampled by fine needle aspiration biopsy.
      Kong CS, Appenzeller M, Ferrell LD| | PubMed