University of California San Francisco

Linda Ferrell - 144
Linda
Ferrell
MD

Emeritus Professor
Departments of Pathology & Laboratory Medicine 

Address

513 Parnassus Avenue, MSB, #001
San Francisco, CA 94143
United States

Email: [email protected]
Phone: 415-353-1090
Fax: 415-353-1200

    Biography

    Linda Ferrell, M.D. is a liver pathologist, Professor of Pathology, Vice Chair of Clinical Services, and Director of Surgical Pathology at UCSF. She specializes in the diagnosis of liver disorders such as: benign liver tumors, cirrhosis, hepatitis B, hepatitis C, hepatocellular carcinoma, vascular lesions, metastastic cancer to the liver, liver transplantation, nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). She graduated summa cum laude from the University of Kansas, where she also attended medical school and completed her residency. Dr. Ferrell went on to complete her surgical pathology fellowship at the University of California, San Francisco, while concurrently serving as Chief Resident. She has been the recipient of numerous awards, published a large number of articles and book chapters and currently serves as a co-editor on two medical textbooks in her field of expertise. In early 2010 she was elected Vice President of the United States and Canadian Academy of Pathology (USCAP). Information pertaining to her awards and published materials can be found on her Curriculum Vitae.

    Education

    Institution Degree Dept or School End Date
    University of Kansas M.D. School of Medicine 1977

    Board Certifications

    • American Board of Pathology, Anatomic Pathology

    Clinical Expertise

    Benign Liver Tumors
    Cirrhosis
    Hepatitis B
    Hepatitis C
    Hepatocellular Carcinoma (Liver Cancer)
    Liver Metastases
    Liver Transplantation
    Nonalcoholic Fatty Liver Disease

    Program Affiliations

    Member, UCSF Helen Diller Family Comprehensive Cancer Center
    UCSF Medical Center Organ Transplant Program

    Research Narrative

    Dr. Ferrell's research interests are primarily liver pathology, with emphasis on liver transplantation, fatty liver, hepatitis B and C and liver tumors, particularly well-differentiated hepatocellular tumors and vascular lesions. She actively participated in the World Congress' Consensus Groups for the nomenclature of nodules in the liver and recommendations for terminology for hepatic allograft rejection. Dr. Ferrell's studies on liver pathology in recurrent hepatitis C after transplantation and on the diagnosis of dysplastic nodules have been recognized internationally as leading papers ion these topics. She was also involved in a recent evaluation and review of benign liver tumors in coordination with the International Liver Pathology Study Group and the Laennec Society. Her current ongoing studies involve unusual variants of tumors (HCC, vascular, others), vascular malformations in the liver and other markers in well-differentiated hepatocellular tumors.

    Research Interests

    • Liver pathology, emphasizing liver transplantation
    • Fatty liver
    • Hepatitis B and C
    • Liver tumors
    • Well-differentiated hepatocellular tumors & vascular lesions

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 235
    1. Diagnostic use of cytokeratins, CD34, and neuronal cell adhesion molecule staining in focal nodular hyperplasia and hepatic adenoma.
      Ahmad I, Iyer A, Marginean CE, Yeh MM, Ferrell L, Qin L, Bifulco CB, Jain D| | PubMed
    2. Is histological diagnosis of primary liver carcinomas with fibrous stroma reproducible among experts?
      Malouf G, Falissard B, Azoulay D, Callea F, Ferrell LD, Goodman ZD, Hayashi Y, Hsu HC, Hubscher SG, Kojiro M, Ng IO, Paterson AC, Reynes M, Zafrani ES, Emile JF| | PubMed
    3. Chromosomal changes in fibrolamellar hepatocellular carcinoma detected by array comparative genomic hybridization.
      Kakar S, Chen X, Ho C, Burgart LJ, Sahai V, Dachrut S, Yabes A, Jain D, Ferrell LD| | PubMed
    4. Frequency and histopathologic basis of hepatic surface nodularity in patients with fulminant hepatic failure.
      Poff JA, Coakley FV, Qayyum A, Yeh BM, Browne LW, Merriman RB, Ferrell LD, Feldstein VA| | PubMed
    5. Liver steatosis: investigation of opposed-phase T1-weighted liver MR signal intensity loss and visceral fat measurement as biomarkers.
      Bahl M, Qayyum A, Westphalen AC, Noworolski SM, Chu PW, Ferrell L, Tien PC, Bass NM, Merriman RB| | PubMed
    6. Post-transplant recurrent hepatitis C: immunohistochemical detection of hepatitis C virus core antigen and possible pathogenic implications.
      Pessôa MG, Alves VA, Wakamatsu A, Gomes JG, Maertens G, van der Borght B, Kim M, Ferrell L, Wright TL| | PubMed
    7. Utility and limitations of glypican-3 expression for the diagnosis of hepatocellular carcinoma at both ends of the differentiation spectrum.
      Shafizadeh N, Ferrell LD, Kakar S| | PubMed
    8. Best practices in diagnostic immunohistochemistry: hepatocellular carcinoma versus metastatic neoplasms.
      Kakar S, Gown AM, Goodman ZD, Ferrell LD| | PubMed
    9. Special stains can distinguish hepatic necrosis with regenerative nodules from cirrhosis.
      Ferrell LD, Greenberg MS| | PubMed
    10. Biliary intraepithelial neoplasia: an international interobserver agreement study and proposal for diagnostic criteria.
      Zen Y, Adsay NV, Bardadin K, Colombari R, Ferrell L, Haga H, Hong SM, Hytiroglou P, Klöppel G, Lauwers GY, van Leeuwen DJ, Notohara K, Oshima K, Quaglia A, Sasaki M, Sessa F, Suriawinata A, Tsui W, Atomi Y, Nakanuma Y| | PubMed