University of California San Francisco

Linda Ferrell, MD

Linda Ferrell - 144
Linda
Ferrell
MD

Emeritus Professor
Departments of Pathology & Laboratory Medicine 

Address

513 Parnassus Avenue MSB
San Francisco, CA 94143
United States

Email: [email protected]

Biography

Linda Ferrell, M.D. is a liver pathologist, Professor of Pathology, Vice Chair of Clinical Services, and Director of Surgical Pathology at UCSF. She specializes in the diagnosis of liver disorders such as: benign liver tumors, cirrhosis, hepatitis B, hepatitis C, hepatocellular carcinoma, vascular lesions, metastastic cancer to the liver, liver transplantation, nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). She graduated summa cum laude from the University of Kansas, where she also attended medical school and completed her residency. Dr. Ferrell went on to complete her surgical pathology fellowship at the University of California, San Francisco, while concurrently serving as Chief Resident. She has been the recipient of numerous awards, published a large number of articles and book chapters and currently serves as a co-editor on two medical textbooks in her field of expertise. In early 2010 she was elected Vice President of the United States and Canadian Academy of Pathology (USCAP). Information pertaining to her awards and published materials can be found on her Curriculum Vitae.

Education

Institution Degree Dept or School End Date
University of Kansas M.D. School of Medicine 1977

Board Certifications

  • American Board of Pathology, Anatomic Pathology

Clinical Expertise

Benign Liver Tumors
Cirrhosis
Hepatitis B
Hepatitis C
Hepatocellular Carcinoma (Liver Cancer)
Liver Metastases
Liver Transplantation
Nonalcoholic Fatty Liver Disease

Program Affiliations

Member, UCSF Helen Diller Family Comprehensive Cancer Center
UCSF Medical Center Organ Transplant Program

Research Narrative

Dr. Ferrell's research interests are primarily liver pathology, with emphasis on liver transplantation, fatty liver, hepatitis B and C and liver tumors, particularly well-differentiated hepatocellular tumors and vascular lesions. She actively participated in the World Congress' Consensus Groups for the nomenclature of nodules in the liver and recommendations for terminology for hepatic allograft rejection. Dr. Ferrell's studies on liver pathology in recurrent hepatitis C after transplantation and on the diagnosis of dysplastic nodules have been recognized internationally as leading papers ion these topics. She was also involved in a recent evaluation and review of benign liver tumors in coordination with the International Liver Pathology Study Group and the Laennec Society. Her current ongoing studies involve unusual variants of tumors (HCC, vascular, others), vascular malformations in the liver and other markers in well-differentiated hepatocellular tumors.

Research Interests

  • Liver pathology, emphasizing liver transplantation
  • Fatty liver
  • Hepatitis B and C
  • Liver tumors
  • Well-differentiated hepatocellular tumors & vascular lesions

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 10
  1. New histopathological terminology for well-differentiated hepatocellular lesions in unusual clinico-pathological scenarios: HCA-like and FNH-like.
    Sempoux C, Alves VA, Arola J, Balabaud C, Bioulac-Sage P, Colombari R, Crawford JM, Dhillon AP, di Tommaso L, Ferrell LD, Gill RM, Guido M, Hameed B, Harada K, Hytiroglou P, Nakanuma Y, Paradis V, Rautou PE, Theise ND, Thung S, Tsui WM, Snover D, Stueck A, Suriawinata A, van Leeuwen DJ, Quaglia A, International Liver Pathology Study Group| | PubMed
  2. Glutamine synthetase staining patterns in cirrhosis.
    Nguyen ED, Ding CC, Umetsu SE, Ferrell LD, Wen KW| | PubMed
  3. Use of orcein as an adjunct stain in the evaluation of advanced liver fibrosis.
    Nguyen ED, Ding CC, Umetsu SE, Choi WT, Ferrell LD, Wen KW| | PubMed
  4. Transcriptomic Analysis of Cirrhosis-Like Hepatocellular Carcinoma Reveals Distinct Molecular Characteristics and Pathologic Staging Implications.
    Van Treeck BJ, Moreira RK, Mounajjed T, Ferrell L, Xue Y, Jessen E, Davila J, Graham RP| | PubMed
  5. The Voronoi theory of the normal liver lobular architecture and its applicability in hepatic zonation.
    Lau C, Kalantari B, Batts KP, Ferrell LD, Nyberg SL, Graham RP, Moreira RK| | PubMed
  6. Hepatocellular adenomas in the Turkish population: reclassification according to updated World Health Organization criteria.
    Deniz K, Umetsu SE, Ferrell L, Yilmaz F, Güllüoglu M, Sagol Ö, Dogusoy GB, Kirimlioglu H, Turhan N, Doran F, Kepil N, Çelikel ÇA, Nart D, Özgüven BY, Ceyran B, Karadag N, Kir G, Erden E, Yilmaz G, Akyol G| | PubMed
  7. Clinicopathological features and outcomes of parenchymal rejection in liver transplant biopsies.
    Fels Elliott DR, Tavakol M, Lucas CH, Sheahon K, Kakar S, Hameed B, Ferrell LD, Gill RM| | PubMed
  8. Utility of DNA flow cytometry in distinguishing between malignant and benign intrahepatic biliary lesions.
    Wen KW, Rabinovitch PS, Wang D, Mattis AN, Ferrell LD, Choi WT| | PubMed
  9. ASS1 Overexpression: A Hallmark of Sonic Hedgehog Hepatocellular Adenomas; Recommendations for Clinical Practice.
    Sala M, Gonzales D, Leste-Lasserre T, Dugot-Senant N, Paradis V, Di Tommaso S, Dupuy JW, Pitard V, Dourthe C, Sciarra A, Sempoux C, Ferrell LD, Clouston AD, Miller G, Yeh MM, Thung S, Gouw ASH, Quaglia A, Han J, Huan J, Fan C, Crawford J, Nakanuma Y, Harada K, le Bail B, Castain C, Frulio N, Trillaud H, Possenti L, Blanc JF, Chiche L, Laurent C, Balabaud C, Bioulac-Sage P, Raymond AA, Saltel F| | PubMed
  10. Malignant transformation of liver fatty acid binding protein-deficient hepatocellular adenomas: histopathologic spectrum of a rare phenomenon.
    Putra J, Ferrell LD, Gouw ASH, Paradis V, Rishi A, Sempoux C, Balabaud C, Thung SN, Bioulac-Sage P| | PubMed