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Sandy Feng, M.D., Ph.D.

  • Professor of Surgery
  • Division of Transplant Surgery
  • Vice Chair for Research

Contact Information

(415) 353-8725 Academic
[email protected] 
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Education

  • Harvard College, B.A., Chemistry, 1979-82
  • Cambridge University, England, Ph.D., Molecular Biology, 1982-85
  • Stanford University School of Medicine, M.D., 1985-90

Residencies

  • Brigham and Women's Hospital, Intern, Surgery, 1990-91
  • Brigham and Women's Hospital, Resident, Surgery, 1991-94
  • Brigham and Women's Hospital, Chief Resident, Surgery, 1994-95

Fellowships

  • University of California, San Francisco, Fellow, Transplant Surgery, 1996-98

Postdoctoral Training

  • Stanford University School of Medicine, Postdoctoral Fellow, Molecular Biology, 1986-88
  • The Whitehead Institute, MIT, Postdoctoral Fellow, Molecular Biology, 1995-96

Board Certifications

  • American Board of Surgery, 1996

Program Affiliations

  • Clinical Fellowship, Division of Transplantation
  • The Liver Center at UCSF
  • Director, Expanded Criteria Donor Kidney Transplant Program, University of California, San Francisco
  • UCSF Hellen Diller Family Comprehensive Cancer Center

Clinical Expertise

  • Expanded Criteria Donor Kidney Transplantation
  • Immunosuppression for Liver Transplantation
  • Kidney Transplantation
  • Liver Transplantation
  • MELD Allocation and Living Donor Liver Transplantation
  • Pancreas Transplantation

Research Interests

  • Defining the Optimal Immunosuppression for Specific Transplant Settings
  • Expanded Criteria Donors
  • Immunosuppression Withdrawal and Identification of a Profile Predictive of Tolerance
  • Immunosuppression Withdrawal for Stable Pediatric Living Donor Liver Transplant Recipients
  • Improving Long-term Outcomes for Liver Transplant Recipients
  • Novel Immunosuppression Strategies for Liver Transplantation
  • Strategies to Decrease Ischemia Reperfusion Injury to Improve Early Graft Function after Kidney Transplantation

Biography

As Professor of Surgery and Director of the Abdominal Transplant Fellowship Program at UCSF, Dr. Sandy Feng performs liver, kidney and pancreas transplants and teaches surgical fellows, residents, and medical students. She received a doctorate in molecular biology from Cambridge University with her Marshall Scholarship and earned her medical degree at Stanford University School of Medicine. She then completed general surgery residency at the Brigham and Women's Hospital in Boston and a transplant fellowship at the University of California, San Francisco.

Dr. Feng has numerous leadership roles, including Councilor for the American Society of Transplant Surgeons, Deputy Editor for the American Journal of Transplantation, former Co-Chair of the Executive Planning Committee for the American Transplant Congress, and current Chair of the Kidney Pancreas Advisory Committee of the American Society of Transplantation. She has been an invited organizer or participant in several national consensus conferences addressing issues critical to the transplantation community.

Research Overview

Dr. Feng's research interest focuses on transplant immunology, with a particular focus on determinants of organ tolerance. She is also investigating novel immunosuppressive regimens and pursuing immunosuppression withdrawal in selected liver transplant recipients. By studying the immune profiles of transplant patients who are successfully weaned from immunosuppressants, she and her group hope to predict prospectively which patients may be good candidates for immunosuppression withdrawal.

Research & Funding

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ORCID iD: 0000-0002-2601-4350 Additional info
  • PROSPECTIVE LONGITUDINAL STUDY OF IWITH SCREEN FAILURES SECONDARY TO HISTOPATHOLOGY
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    Aug 2017
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    Jul 2020
    Principal Investigator
  • Donor-Alloantigen-Reactive Regulatory T Cell Therapy in Liver Transplantation
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    Jun 2014
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    May 2019
    Principal Investigator
  • Polyclonal Tregs to Promote Tolerance in Pediatric Liver Transplant Recipients
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    Feb 2013
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    Jan 2018
    Principal Investigator
  • Immunosuppression Withdrawal for Stable Pediatric Liver Transplant Recipients
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    Jul 2012
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    Jun 2017
    Principal Investigator
  • "Donor-Specific Regulatory T Cell Therapy in Liver Transplantation"
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    Apr 2012
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    Mar 2014
    Principal Investigator
  • Donor-Specific Regulatory T Cell Therapy in Liver Transplantation
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    Apr 2012
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    Mar 2014
    Principal Investigator

Clinical Trials

Data provided by UCSF Profiles, powered by CTSI

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 123
Data provided by UCSF Profiles, powered by CTSI
  1. Meier RPH, Nunez M, Syed SM, Feng S, Tavakol M, Freise CE, Roberts JP, Ascher NL, Hirose R, Roll GR. DCD liver transplant in patients with a MELD over 35. Front Immunol. 2023; 14:1246867. View in PubMed
  2. Dixon W, Perito ER, Bucuvalas J, Feng S. Mapping children by ALT 4-5 years after liver transplant: Potential individual and population applications. Pediatr Transplant. 2023 09; 27(6):e14569. View in PubMed
  3. Klepper A, Kung A, Vazquez SE, Mitchell A, Mann S, Zorn K, Avila-Vargas I, Kari S, Tekeste M, Castro J, Lee B, Duarte M, Khalili M, Yang M, Wolters P, Price J, Perito E, Feng S, Maher JJ, Lai J, Weiler-Normann C, Lohse AW, DeRisi J, Tana M. Novel autoantibody targets identified in patients with autoimmune hepatitis (AIH) by PhIP-Seq reveals pathogenic insights. medRxiv. 2023 Jun 27. View in PubMed
  4. Chapman WC, Barbas AS, D'Alessandro AM, Vianna R, Kubal CA, Abt P, Sonnenday C, Barth R, Alvarez-Casas J, Yersiz H, Eckhoff D, Cannon R, Genyk Y, Sher L, Singer A, Feng S, Roll G, Cohen A, Doyle MB, Sudan DL, Al-Adra D, Khan A, Subramanian V, Abraham N, Olthoff K, Tekin A, Berg L, Coussios C, Morris C, Randle L, Friend P, Knechtle SJ. Normothermic Machine Perfusion of Donor Livers for Transplantation in the United States - A Randomized Controlled Trial. Ann Surg. 2023 Jun 26. View in PubMed
  5. Dixon W, Sheetz K, Adelmann D, Bokoch M, Reddy M, Kothari R, Roberts JP, Syed S, Feng S, Roll G. Real-world implementation of normothermic machine perfusion: A detailed analysis of intraoperative and early postoperative impact. Clin Transplant. 2023 Jun 17; e15049. View in PubMed
  6. View All Publications

Videos

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  1. Liver Transplant in HIV-Positive Patients and Progress in Immunosupression in Liver Transplantation
  2. UCSF Kidney Transplant Update: The Year in Review, What’s New and What’s Hot 2009
  3. The Rising Star Program Donors and Recipients: Finding the Perfect Match

In the News

  • Sandy Feng, MD, PhD Recipient of 2020 AST Clinical Science Established Investigator Award

    UCSF Department of Surgery - Richard Barg - July 01, 2020
    Sandy Feng, M.D., Ph.D., Professor of Surgery and Vice Chair for Research in the Department of Surgery, has been named the 2020 recipient of the Clinical Science Established Investigator Award from the American Society of Transplantation (AST). The award is made to a senior clinical scientist who has made significant contributions to the field of transplantation and is recognized as an expert. Dr. Feng is a surgeon-scientist with a stellar record of clinical research and outreach to the [...]

  • Dr. Sandy Feng Named Next AJT Editor-in-Chief by ASTS and AST

    UCSF Department of Surgery - Richard Barg - February 11, 2020
    The Department of Surgery congratulates transplant surgeon Sandy Feng, M.D., Ph.D., Professor of Surgery and Vice Chair for Research in the Department of Surgery, on being named the next Editor-in-Chief of the American Journal of Transplantation (AJT). The full joint news release from ASTS and AST appears below: Feb 07, 2020 On behalf of the American Society of Transplantation and the American Society of Transplant Surgeons, we are pleased to announce the selection of Sandy Feng, MD, PhD, [...]

  • Sandy Feng, M.D., Ph.D. Named Inaugural Vice Chair for Research by Department of Surgery

    UCSF Department of Surgery - Richard Barg - July 22, 2019
    Sandy Feng, M.D., Ph.D., Professor of Surgery at the University of California San Francisco (UCSF), has been appointed the inaugural Vice Chair for Research in the Department of Surgery. In her new role, Dr. Feng will serve as a leader in advancing the research mission of the Department, with particular focus on deepening and broadening the Department's research portfolio, including basic and translational science, education and clinical/health services research, and innovation [...]

  • Department of Surgery Ranks 3rd Nationally in NIH Funding for Surgery Category - Three Surgeon-Scientists Rank in Top 20

    UCSF Department of Surgery - Richard Barg - March 27, 2018
    The UCSF Department of Surgery now ranks No. 3 nationally in NIH research funding among all academic surgery programs, a stunning rise from 6th the last time the survey was done. Three Department of Surgery faculty also ranked in the top 20 of all NIH-funded principal investigators nationally in the category of surgery. The highly respected Blue Ridge Institute for Medical Research utilized data from the Research Portfolio Online Reporting Tool (RePORT) to survey U.S. medical schools for their [...]

  • Transplant Surgeons Sandy Feng and Peter Stock Rank in Top 20 of NIH-Funded Investigators in Surgery for 2017

    UCSF Department of Surgery - Richard Barg - March 12, 2018
    Transplant surgeons Sandy Feng, M.D., Ph.D. and Peter G. Stock, M.D., Ph.D. continued their stellar records of accomplishment in garnering NIH funding for their cutting-edge clinical research, ranking in the top 20 of all NIH-Funded principal investigators in the category of surgery nationally for 2017. Stock ranked 8th and Feng 20th out of 534 investigators nationwide, both in the top 4%, this according to survey data analyzed by the highly respected Blue Ridge Institute for Medical Research. [...]

  • Donor-Intervention Research Slowed Amidst Issues of Informed Consent and Conflicts Among Disparate IRBs

    UCSF Transplant Surgery - Richard Barg - August 16, 2017
    The Atlantic reports on the difficulties in the current climate of conducting donor-intervention research due to issues of informed consent, disagreements over what constitutes human subject research, and conflicting views of Institutional Review Boards (IRB) spread across multiple centers with patients putatively impacted by the research protocol. Moreover, doctors must test the experimental interventions designed to improve outcomes within the crucible of a short time window, given that a [...]

  • UCSF Transplant Surgeon Dr. Sandy Feng to Lead Consensus Conference on Kidney Paired Donation (KPD)

    UCSF Transplant Surgery - February 18, 2012
    In excess of 90,000 people are on the waiting list for kidney transplants, fewer than 17,000 receive one each year, and about 4,500 die on the waiting list. Even where a relative or friend is willing to donate a kidney, the kidney may not be a biological match. To address this problem, paired kidney exchange programs were created. Although it has been more than a decade since the first paired kidney exchange took place in the US, there is still no uniform system for these exchanges. Sandy Feng, [...]

 

 
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