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Transplant Surgery »  Meet the Team »  Transplant Surgeons »  Nancy L. Ascher, M.D., Ph.D.

Nancy L. Ascher, M.D., Ph.D.

Professor of Surgery
Division of Transplant Surgery
Isis Distinguished Professor in Transplantation


Contact Information

Academic Office
415-353-9321
nancy.ascher@ucsf.edu
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  • University of Michigan, Ann Arbor, MI, B.A., 1967-70
  • University of Michigan Medical School, Ann Arbor, MI, M.D., 1970-74
  • University of Minnesota, Minneapolis, MN, Ph.D., 1974-85
  • University of Minnesota, Department of Surgery, Minneapolis, MN,  Surgical Internship, 1974-75
  • University of Minnesota, Department of Surgery, Minneapolis, MN, Surgical Residency, 1975-77
  • University of Minnesota, Department of Surgery, Minneapolis, MN, Surgical Residency, 1979-81
  • University of Minnesota, Department of Surgery, Minneapolis, MN,   Transplant Fellowship, 1981-1982
  • University of Minnesota, Department of Surgery, Minneapolis, MN, Research Fellowship, 1977-79
  • American Board of Surgery, 1982, renewed 2012
  • End-Stage Kidney Disease
  • Fulminant Hepatic Failure
  • Hepatitis B
  • Hepatitis C
  • Hepatocellular Carcinoma (Liver Cancer)
  • Kidney Transplantation
  • Liver Cysts
  • Liver Transplantation
  • Living Donor Liver Transplantation
  • Living Donor Kidney Transplantation
  • Non-alcoholic Fatty Liver Disease
  • Pediatric Kidney Transplantation
  • Pediatric Liver Transplantation
  • Portal Hypertension
  • Clinical Transplantation
  • Recurrence After Liver Transplantation
  • Transplant Ethics
  • Transplant Policy

Dr. Nancy Ascher has devoted her career to organ transplants and transplant research. Dr. Ascher completed her undergraduate and medical education at the University of Michigan, Ann Arbor. She then went on to complete a general surgery residency and clinical transplantation fellowship at the University of Minnesota. 

Dr. Ascher joined the faculty of the Department of Surgery at the University of Minnesota in 1982 and was named Clinical Director of the Liver Transplant Program. She was recruited in 1988 by the UCSF Department of Surgery to build a liver transplantation program. In 1991, she was appointed Chief of Transplantation, an expanded role that included liver, kidney and pancreas transplants.

In 1993, Dr. Ascher was appointed Vice-Chair of the UCSF Department of Surgery, and in 1999 was appointed Department Chair where she served until September 2016.

Dr. Ascher has had a distinguished career of public service that includes appointments to the Presidential Task Force on Organ Transplantation and the Surgeon General's Task Force on Increasing Donor Organs. She also served as Chair of the Advisory Committee on Organ Transplantation for the Secretary of Health and Human Services from 2001 - 2005. Highly respected by her peers, Dr. Ascher was named to the list of U.S. News "America's Top Doctors," a distinction reserved for the top 1% of physicians in the nation for a given specialty.

Dr. Ascher is a Fellow of the American College of Surgeons and holds memberships in numerous other medical societies. She has taken an active leadership role in American Society of Transplant Surgeons activities and was its past-president. Dr. Ascher has published over 425 articles in medical and scientific journals. Her research interests are in hepatocyte immunogenicity, mechanisms of allograft rejection and clinical transplantation.

I. RECURRENT DISEASE AFTER LIVER TRANSPLANT
The NIH Liver Transplant Data Base has been extended to address the important issue of disease recurrence after liver transplantation. Although short term liver transplant results have improved markedly over the past ten years, it is apparent that disease recurrence is an important source of patient morbidity and graft loss. Long term following of greater than 1000 patients in the Liver Transplant Data Base will facilitate our understanding of the factors associated with graft recurrence.

II. EXPANDED CRITERIA FOR LIVER TRANSPLANT FOR HEPATOCELLULAR CARCINOMA
We have redefined the criteria for liver transplantation beyond the Milan criteria. The UCSF criteria enables additional patients to benefit from liver transplants without compromising outcome.

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  • LIVER TRANSPLANTATION CENTERS
    Sponsor:
    Sponsor ID:
    Funding Period:
    Jan 1990
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    Dec 1997
    Principal Investigator
  • ALLOGRAFT RESPONSE TO LIVER TISSUE
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    Funding Period:
    Sep 1988
    -
    Sep 1995
    Principal Investigator
  • ORGAN TRANSPLANTS: ANALYSIS OF MIGRATING LYMPHOCYTES
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    Funding Period:
    Jul 1984
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    Jun 1987
    Principal Investigator
MOST RECENT PUBLICATIONS FROM A TOTAL OF 389
Data provided by UCSF Profiles, powered by CTSI
  1. Braun HJ, Ascher NL. Training of Male and Female Surgical Residents. JAMA Surg. 2020 Jul 29. View in PubMed
  2. Lebares CC, Coaston TN, Delucchi KL, Guvva EV, Shen WT, Staffaroni AM, Kramer JH, Epel ES, Hecht FM, Ascher NL, Harris HW, Cole SW. Enhanced Stress Resilience Training in Surgeons: Iterative Adaptation and Biopsychosocial Effects in 2 Small Randomized Trials. Ann Surg. 2020 Jul 08. View in PubMed
  3. Schwab ME, Braun HJ, Ascher NL, Hirose R. Implementing an opioid reduction protocol in renal transplant recipients. Am J Surg. 2020 Jul 01. View in PubMed
  4. Delmonico FL, Dominguez-Gil B, Ascher NL, Glazier AK, Henderson GV, Bernat JL. Author's Response. Transplantation. 2020 Jul; 104(7):e218-e219. View in PubMed
  5. Syed SM, Gardner J, Roll G, Webber A, Mehta N, Shoji J, Adelmann D, Niemann C, Braun HJ, Mello A, Yao F, Posselt A, Kang SM, Hirose R, Roberts J, Feng S, Ascher N, Stock P, Freise C. COVID-19 and Abdominal Transplant: A Stepwise Approach to Practice During Pandemic Conditions. Transplantation. 2020 Jun 29. View in PubMed
  6. View All Publications
  • Gloria & Veronica Ramos

    Living Donor Transplant Emblemmatic of Loving Family

    Gloria Ramos
    When Gloria Ramos received the call in August 2000 that UCSF Medical Center had a liver for the transplant she badly needed, the Ramos family drove to the hospital with great anticipation and excitement. But further testing of the available organ revealed it wasn't a good match for Gloria and her daughters and husband expressed their disappointment. "This only means that I'm at the top of the list," Gloria recalls assuring her family. "I'll get called again!" Gloria contracted Hepatitis C through a blood transfusion in 1982 but the deadly virus lived undetected in her body until the summer[...]
    Story Categories: CirrhosisHepatitis CLiver TransplantLiving Donor Liver Transplant

 

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