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James M. Gardner, M.D., Ph.D.

James M. Gardner, M.D., Ph.D.

  • Assistant Professor of Surgery
  • Division of Transplant Surgery

Contact Information

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Harvard University, B.A., Biochemical Sciences, 2002
University of California San Francisco, M.D., Ph.D. 2012
  • University of California San Francisco, Intern, General Surgery, 2012-2013
  • University of California San Francisco, Resident, General Surgery, 2013-2016
  • University of California San Francisco, Chief Resident, General Surgery, 2016-2017
  • University of California San Francisco, Abdominal Transplant Clinical Fellow, 2017-2019
  • American Board of Surgery, General Surgery
  • UCSF Department of Surgery
  • UCSF Division of Transplant Surgery
  • UCSF Diabetes Center
  • Ascites
  • Bile Duct Cancer (Cholangiocarcinoma)
  • Bile Duct Injuries
  • Bile Duct Strictures
  • Bridging Therapies to Downstage HCC in Liver Transplant Setting
  • Choledochal Cysts
  • Deceased Donor Organ Utilization
  • Gallbladder Cancer
  • Hepatocellular Carcinoma (Primary Liver Cancer)
  • Kidney Transplantation
  • Laparoscopic Donor Nephrectomy
  • Liver Biopsy
  • Liver Cysts
  • Liver Metastases (Secondary Liver Cancer)
  • Liver Resection
  • Liver Transplantation
  • Living Donor Kidney Transplantation
  • Living Donor Liver Transplantation
  • Normothetic Machine Liver Perfusion
  • Organ Donation of Cardiovascular Death
  • Pancreas Transplantation
  • Pediatric Kidney Transplantation
  • Pediatric Liver Transplantation
  • Portal Hypertension
  • Immune tolerance
  • Autoimmmune diabetes
  • Transplant surgery
  • Spanish

James M. Gardner, M.D., Ph.D. is an Assistant Professor in the Division of Transplant Surgery and a transplant surgeon who performs kidney, liver and pancreas transplants for both adults and children. 

Dr. Gardner earned his B.A. from Harvard University in Biochemical Sciences and his M.D. and Ph.D. degrees from UCSF. He then completed his General Surgery Residency at UCSF followed by a two-year clinical fellowship in Transplant Surgery.

Recently, Dr. Gardner was awarded an appointment to the prestigious Physician-Scientist Scholar Program (PSSP), only one of which is given per year among all departments in the School of Medicine, and provides direct research funding to support early-career scientists. Dr. Gardner is the first surgeon to receive this award, part of the UCSF Sandler Fellows Program. 

  Award  
  Confired By    
  Date    
  • Sander PSSP Grant
  • UCSF Dean's Office
  • 2019 - 2024
  • Sandler PSSP Grant
  • UCSF Dean's Office
  • 2019 - 2024
  • ASTS-Astellas Fellowship in Transplantation Grant
  • American Society of Transplant Surgeons
  • 2017 - 2019
  • Nusz Achievement Award
  • UCSF Department of Surgery
  • 2017 - 2017
  • Schecter Award for Senior Trauma Fellow
  • UCSF Division of Trauma and Critical Care
  • 2016 - 2016
  • ED Surgical Consultant of the Year
  • UCSF Emergency Medicine
  • 2016 - 2016
  • Dr. Gardner's research is focused on the mechanisms regulating self-tolerance in the adaptive immune system, and translating these findings into relevant therapeutics for inducing and maintaining donor-specific tolerance. In mentored collaboration with the Mark Anderson lab at the UCSF Diabetes Center, Dr. Gardner's studies focus on a gene called the Autoimmune Regulator, or Aire, which is a key regulator of central tolerance. Dr. Gardner and Dr. Anderson have defined a novel population of extrathymic Aire-expressing cells (eTACs), and their work focuses on the role of this population in autoimmunity and tolerance.
    MOST RECENT PUBLICATIONS FROM A TOTAL OF 30
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    1. Kedmi R, Najar TA, Mesa KR, Grayson A, Kroehling L, Hao Y, Hao S, Pokrovskii M, Xu M, Talbot J, Wang J, Germino J, Lareau CA, Satpathy AT, Anderson MS, Laufer TM, Aifantis I, Bartleson JM, Allen PM, Paidassi H, Gardner JM, Stoeckius M, Littman DR. A ROR?t+ cell instructs gut microbiota-specific Treg cell differentiation. Nature. 2022 Sep 07. View in PubMed
    2. Sitta R, Roberts J, Gardner J, Ascher N, Piper M. A novel microsurgical reconstruction technique in a living-related liver donor hepatic artery dissection using the native hepatic artery. Am J Transplant. 2022 May 25. View in PubMed
    3. Chen AK, Lunow-Luke T, Yamaguchi S, Praglin C, Agudelo E, Mehta N, Dirks R, Braun HJ, Gardner JM, Roberts JP, Syed SM, Roll GR. Nodular Regenerative Hyperplasia After Liver Transplant; It's All in the Presentation. Front Surg. 2022; 9:876818. View in PubMed
    4. Tabula Sapiens Consortium*, Jones RC, Karkanias J, Krasnow MA, Pisco AO, Quake SR, Salzman J, Yosef N, Bulthaup B, Brown P, Harper W, Hemenez M, Ponnusamy R, Salehi A, Sanagavarapu BA, Spallino E, Aaron KA, Concepcion W, Gardner JM, Kelly B, Neidlinger N, Wang Z, Crasta S, Kolluru S, Morri M, Pisco AO, Tan SY, Travaglini KJ, Xu C, Alcántara-Hernández M, Almanzar N, Antony J, Beyersdorf B, Burhan D, Calcuttawala K, Carter MM, Chan CKF, Chang CA, Chang S, Colville A, Crasta S, Culver RN, Cvijovic I, D'Amato G, Ezran C, Galdos FX, Gillich A, Goodyer WR, Hang Y, Hayashi A, Houshdaran S, Huang X, Irwin JC, Jang S, Juanico JV, Kershner AM, Kim S, Kiss B, Kolluru S, Kong W, Kumar ME, Kuo AH, Leylek R, Li B, Loeb GB, Lu WJ, Mantri S, Markovic M, McAlpine PL, de Morree A, Morri M, Mrouj K, Mukherjee S, Muser T, Neuhöfer P, Nguyen TD, Perez K, Phansalkar R, Pisco AO, Puluca N, Qi Z, Rao P, Raquer-McKay H, Schaum N, Scott B, Seddighzadeh B, Segal J, Sen S, Sikandar S, Spencer SP, Steffes LC, Subramaniam VR, Swarup A, Swift M, Travaglini KJ, Van Treuren W, Trimm E, Veizades S, Vijayakumar S, Vo KC, Vorperian SK, Wang W, Weinstein HNW, Winkler J, Wu TTH, Xie J, Yung AR, Zhang Y, Detweiler AM, Mekonen H, Neff NF, Sit RV, Tan M, Yan J, Bean GR, Charu V, Forgó E, Martin BA, Ozawa MG, Silva O, Tan SY, Toland A, Vemuri VNP, Afik S, Awayan K, Botvinnik OB, Byrne A, Chen M, Dehghannasiri R, Detweiler AM, Gayoso A, Granados AA, Li Q, Mahmoudabadi G, McGeever A, de Morree A, Olivieri JE, Park M, Pisco AO, Ravikumar N, Salzman J, Stanley G, Swift M, Tan M, Tan W, Tarashansky AJ, Vanheusden R, Vorperian SK, Wang P, Wang S, Xing G, Xu C, Yosef N, Alcántara-Hernández M, Antony J, Chan CKF, Chang CA, Colville A, Crasta S, Culver R, Dethlefsen L, Ezran C, Gillich A, Hang Y, Ho PY, Irwin JC, Jang S, Kershner AM, Kong W, Kumar ME, Kuo AH, Leylek R, Liu S, Loeb GB, Lu WJ, Maltzman JS, Metzger RJ, de Morree A, Neuhöfer P, Perez K, Phansalkar R, Qi Z, Rao P, Raquer-McKay H, Sasagawa K, Scott B, Sinha R, Song H, Spencer SP, Swarup A, Swift M, Travaglini KJ, Trimm E, Veizades S, Vijayakumar S, Wang B, Wang W, Winkler J, Xie J, Yung AR, Artandi SE, Beachy PA, Clarke MF, Giudice LC, Huang FW, Huang KC, Idoyaga J, Kim SK, Krasnow M, Kuo CS, Nguyen P, Quake SR, Rando TA, Red-Horse K, Reiter J, Relman DA, Sonnenburg JL, Wang B, Wu A, Wu SM, Wyss-Coray T. The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans. Science. 2022 05 13; 376(6594):eabl4896. View in PubMed
    5. Sun IH, Gillis-Buck E, Mackenzie TC, Gardner JM. Thymic and extrathymic Aire-expressing cells in maternal-fetal tolerance. Immunol Rev. 2022 07; 308(1):93-104. View in PubMed
    6. View All Publications
    1. Gardner et al., American Transplant Congress, 2015. Outcomes in a new category of Pancreas-After-Islet Transplantation.
    2. Gardner et al., UCSF Surgery Resident Research Symposium, 2013-2016. Extrathymic Aire-Expressing Cells in Immune Tolerance and Transplantation.
    3. Gardner et al., International Pancreas and Islet Transplant Association 2013. Outcomes in a new category of Pancreas-After-Islet Transplantation.
    4. Gardner et al., Children?s Diabetes Foundation of the North Bay Annual Retreat, 2010. Novel Approaches for Preventing and Treating Juvenile Diabetes: What?s on the Horizon?
    5. Gardner et al., Kyoto T Cell Conference 2009. Extrathymic Aire-Expressing Cells and the Maintenance of Immunologic Tolerance.
    6. Gardner et al., American Diabetes Association Tour de Cure Donors? Evening, 2008. New approaches to Preventing and Treating Autoimmune Diabetes.
    7. Gardner et al., UCSF/UCB 2008 Immunology Retreat. Phenotypic and Functional Characterization of Extrathymic Aire-Expressing Cells.
    1. Gardner JM, Anderson MS. The Mouse Model of Autoimmune Polyglandular Syndrome Type I. Immunoendocrinology: Scientific and Clinical Aspects. 1st edition. Ed. Eisenbarth G. (New York: Humana Press, 2011.)

     

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