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Garrett R. Roll, M.D., FACS

Garrett R. Roll, M.D., FACS

Assistant Professor of Surgery
Division of Transplant Surgery

Contact Information

Academic Office
(415) 353-8725
garrett.roll@ucsf.edu
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  • Boston College, BS, Finance, 1995-1999
  • Brandeis University, Post Baccalaureate, Premedical, 1999-2001
  • Temple University School of Medicine, MD, 2001-2005
  • University of California, San Francisco, General Surgery, 2005-2012
  • UCSF Department of GI Hepatology Research Fellowship
  • University of California, San Francisco, Abdominal Transplant Surgery, 2012-2014
  • Senior international Fellow in liver transplant and retrieval, Queen Elizabeth Hospital, Birmingham, England
  • American Board of Surgery, General Surgery
  • Transplantation
  • HBP surgery
  • Ascites
  • Bile Duct Cancer (Cholangiocarcinoma)
  • Bile Duct Injuries
  • Bile Duct Strictures
  • Bridging Therapies to Downstage HCC in Liver Transplant Setting
  • Choledochal Cysts
  • Deceased Donor Organ Utilization
  • Gallbladder Cancer
  • Hepatocellular Carcinoma (Primary Liver Cancer)
  • Kidney Transplantation
  • Laparoscopic Donor Nephrectomy
  • Liver Biopsy
  • Liver Cysts
  • Liver Metastases (Secondary Liver Cancer)
  • Liver Resection
  • Liver Transplantation
  • Living Donor Kidney Transplantation
  • Living Donor Liver Transplantation
  • Normothetic Machine Liver Perfusion
  • Organ Donation of Cardiovascular Death
  • Pancreas Transplantation
  • Pediatric Kidney Transplantation
  • Pediatric Liver Transplantation
  • Portal Hypertension
  • Cell therapy with hepatocytes and hepatocyte-like cells derived from stem cells.
  • Normothetic machine liver perfusion
  • Role of miRNA in liver regeneration

Dr. Roll is a general surgeon specializing in abdominal organ transplantation. He completed both general surgery training and the abdominal organ transplant fellowship at the University of California San Francisco. 

During his training, Dr. Roll spent 2 years in Dr. Holger Willenbring's laboratory investigating stem cell biology in the context of liver cell therapy, as well as normal and pathologic liver regeneration. His research concentrated on the use of hepatocyte-like cells derived from stem cells to be used in liver cell therapy. In particular, Dr. Roll investigated the regenerative capabilities of hepatocytes derived from induced pluripotent stem (iPS) cells. They used a genetically deficient mouse model of liver disease as a way to test the functional capabilities of these cells after transplantation. They were able to demonstrate that the profound proliferative capabilities of adult hepatocytes are retained by hepatocytes derived from iPS cells, and transplanting these cells rescued mice with liver failure. Dr. Roll also investigated the role of miRNA in liver regeneration, and the rejection of transplanted hepatocytes and hepatocyte-like cells. The principles of his research will remain valuable in liver and pancreas cell therapy translational science for years.

After fellowship Dr. Roll moved to England to become a Senior International Fellow in Liver Transplant and Multi Organ Procurement at Queen Elizabeth Hospital, Birmingham, one of the busiest liver transplant departments in the United Kingdom. There he gained valuable experience in the blossoming field of normothermic machine liver perfusion prior to returning to UCSF. 

Most recent publications from a total of 56
  1. Ku E, Lee BK, McCulloch CE, Roll GR, Grimes B, Adey D, Johansen KL. Racial and Ethnic Disparities in Kidney Transplant Access within a Theoretical Context of Medical Eligibility. Transplantation. 2019 Sep 13. View in PubMed
  2. Crow LD, Jambusaria-Pahlajani A, Chung CL, Baran DA, Lowenstein SE, Abdelmalek M, Ahmed RL, Anadkat MJ, Arcasoy SM, Berg D, Bibee KP, Billingsley E, Black WH, Blalock TW, Bleicher M, Brennan DC, Brodland DG, Brown MR, Carroll BT, Carucci JA, Chang TW, Chaux G, Cusack CA, Dilling DF, Doyle A, Emtiazjoo AM, Ferguson NH, Fosko SW, Fox MC, Goral S, Gray AL, Griffin JR, Hachem RR, Hall SA, Hanlon AM, Hayes D, Hickey GW, Holtz J, Hopkins RS, Hu J, Huang CC, Brian Jiang SI, Kapnadak SG, Kraus ES, Lease ED, Leca N, Lee JC, Leitenberger JJ, Lim MA, Longo MI, Malik SM, Mallea JM, Menter A, Myers SA, Neuburg M, Nijhawan RI, Norman DJ, Otley CC, Paek SY, Parulekar AD, Patel MJ, Patel VA, Patton TJ, Pugliano-Mauro M, Ranganna K, Ravichandran AK, Redenius R, Roll GR, Samie FH, Shin T, Singer JP, Singh P, Soon SL, Soriano T, Squires R, Stasko T, Stein JA, Taler SJ, Terrault NA, Thomas CP, Tokman S, Tomic R, Twigg AR, Wigger MA, Zeitouni NC, Arron ST. Initial skin cancer screening for solid organ transplant recipients in the United States: Delphi method development of expert consensus guidelines. Transpl Int. 2019 Dec; 32(12):1268-1276. View in PubMed
  3. Roll GR, Webber AB, Gae DH, Laszik Z, Tavakol M, Mayen L, Cunniffe K, Syed S, Hirose R, Freise C, Feng S, Roberts JP, Ascher NL, Stock PG, Rajalingam R. A virtual crossmatch based strategy facilitates sharing of deceased donor kidneys for highly sensitized recipients. Transplantation. 2019 Aug 19. View in PubMed
  4. Braun HJ, Dodge JL, Grab JD, Syed SM, Roll GR, Freise CE, Roberts JP, Ascher NL. Living Donor Liver Transplant for Alcoholic Liver Disease: Data from the Adult to Adult Living Donor Liver Transplantation Study (A2ALL). Transplantation. 2019 May 15. View in PubMed
  5. Feinstein MA, Marcus SG, Amara DP, Durcanova B, Roll GR, Orandi BJ. The effect of an organ procurement experience on preclinical medical student perceptions of transplant surgery. Clin Transplant. 2019 Apr; 33(4):e13505. View in PubMed
  6. Gao Y, Twigg AR, Hirose R, Roll GR, Nowacki AS, Maytin EV, Vidimos AT, Rajalingam R, Arron ST. Association of HLA Antigen Mismatch With Risk of Developing Skin Cancer After Solid-Organ Transplant. JAMA Dermatol. 2019 Mar 01; 155(3):307-314. View in PubMed
  7. Adelmann D, Roll GR, Kothari R, Syed S, Burdine LJ, Tavakol M, Niemann CU. The Impact of Deceased Donor Liver Extraction Time on Early Allograft Function in Adult Liver Transplant Recipients. Transplantation. 2018 Nov; 102(11):e466-e471. View in PubMed
  8. Juszczak H, Lowenstein SE, Crow L, Roll GR, McCalmont TH, Arron ST. Potential for overlooked melanoma in solid organ donors with a severely dysplastic nevus. JAAD Case Rep. 2018 Aug; 4(7):682-683. View in PubMed
  9. Hillary J. Braun, Garrett R. Roll, John Paul Roberts. Adult Living-Donor Liver Transplantation: Left Lobe. Liver Transplantation. 2018 Jul 1; 151-168. View in PubMed
  10. Hillary Braun, Jennifer L. Dodge, Josh D. Grab, Shareef M. Syed, Garrett R. Roll, Chris E. Freise, John P. Roberts, Nancy L. Ascher. Living Donor Liver Transplantation for Alcoholic Liver Disease. Transplantation Journal. 2018 Jul 1; 102(&NA;):s22-s23. View in PubMed
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Please note: UCSF Profiles publications are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact CTSI for help.

 

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