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Philip Rosenthal, M.D.
- Professor of Pediatrics and Surgery Director of Pediatric Hepatology Research Director, Pediatric Hepatology
Contact Information
| Academic Office Room MU 415, Box 0136 University of California, San Francisco San Francisco, CA 94143-0136 (415) 476-5892 (415) 476-1343 Fax prosenth@peds.ucsf.edu |
Education
1967-71 State Univ. of N.Y. at Albany, Albany, NY, B.S. Magna Cum Laude, Biology
1971-75 State Univ. of N.Y. Downstate Med. Ctr. Brooklyn, NY, M.D. Magna Cum Laude
Residencies
- 1975-76 Albert Einstein/Bronx Mun. Hosp., NY, Intern Pediatrics
- 1976-78 Albert Einstein/Bronx Mun. Hosp., NY, Resident Pediatrics
Clinical Expertise
- Acute Liver Failure
- Biliary Atresia
- Bioartificial Liver Support
- Choledochal Cyst
- Cirrhosis
- Hepatitis B
- Hepatitis C
- Hepatocellular Carcinoma (Liver Cancer)
- Live Donor Liver Transplantation
- Liver Transplantation
- Neonatal Hepatitis
Biography
Philip Rosenthal, M.D. is Professor of Pediatrics and Surgery, Medical Director of the Pediatric Liver Transplant Program. and Director of Pediatric Hepatology at UCSF. Rosenthal completed his medical training at Downstate Medical Center and the Albert Einstein Medical Center in New York. He then completed a fellowship in pediatric gastroenterology at UCSF. He joined the UCSF faculty in 1995 after serving as Professor of Pediatrics at University of California, Los Angeles (UCLA).
A pediatric hepatologist at the UCSF Benioff Children's Hospital, Rosenthal is internationally renowned for the care of children with liver disease, including liver cancer, and those undergoing liver transplantation. In addition, Rosenthal has and currently serves as Principal Investigator on numerous clinical trials to improve the care of patients with pediatric liver disease.
Rosenthal has won numerous honors for his research including work on the pharmaceutical treatment of hepatitis B and C, genetics and immunology of biliary atresia and the quality of life after liver transplants in children. He is a consultant to organizations such as the American Liver Foundation, Parents of Kids with Infectious Diseases, Alagille Syndrome Alliance, Studies of Pediatric Liver Transplantation (SPLIT), Centers for Disease Control and Prevention (CDC) and the National Institutes of Health (NIH). He is also on editorial boards and a regular reviewer for leading professional journals.
Awards & Honors
Award
Confired By
Date
Research Overview
Rosenthal is pursuing research on the pharmaceutical treatment of hepatitis B and C, genetics and immunology of biliary disease, use of bioartificial liver support utilizing porcine hepatocytes for patients with fulminant liver failure, as well as researching the quality of life following liver transplantation in children.
Clinical Research
Rosenthal is principal investigator on numerous clinical trials including the following:
- Tenofovir Alafenamide (TAF) in Adolescents With Chronic Hepatitis B Virus Infection
- NAFLD Pediatric Database 2
- A Study to Evaluate Treatment of Hepatitis C Virus Infection in Pediatric Subjects
- A Study to Evaluate the Pharmacokinetics, Safety, and Efficacy of Glecaprevir/Pibrentasvir in Pediatric Subjects With Genotypes 1-6 Chronic Hepatitis C Virus (HCV) Infection
Research & Funding
Data provided by UCSF Profiles, powered by CTSI
- Optimal chemopreventive regimens to prevent malaria and improve birth outcomes in UgandaSponsor: NIH/NIAIDSponsor ID: U01AI141308Funding Period:Apr 2020-Mar 2025Co-Principal Investigator
- Childhood Liver Disease Research Network (ChiLDReN) - UCSF (CC)Sponsor: NIH/NIDDKSponsor ID: U01DK062500Funding Period:Sep 2002-May 2024Principal Investigator
- Mechanisms of varied sensitivity of P. falciparum field isolates to the antimalarial drug pipelineSponsor: NIH/NIAIDSponsor ID: R01AI139179Funding Period:Jun 2018-May 2023Principal Investigator
Publications
MOST RECENT PUBLICATIONS FROM A TOTAL OF 388
Data provided by UCSF Profiles, powered by CTSI
- Gonzalez-Peralta RP, Wirth S, Squires RH, Mutschler F, Lang T, Pawlowska M, Sluzewski W, Majda-Stanislawska E, Fischler B, Balistreri WF, Jonas MM, Blondet N, Rosenthal P, Alkhouri N, Romero R, Grandhi A, Castronuovo P, Caro L, Du L, Rosenbloom DIS, Haber BA. Elbasvir/grazoprevir in children aged 3-18 years with chronic HCV genotype 1 or 4 infection: a pharmacokinetic modeling study. Hepatol Commun. 2023 Mar 01; 7(3):e0031. View in PubMed
- Miloh T, Goldstein A, Howard R, Mogul DB, Marden JR, Anderson A, Gaburo K, Kirson N, Rosenthal P. Costs of pediatric liver transplantation among commercially- and medicaid-insured patients with cholestasis in the United States. Liver Transpl. 2023 Feb 08. View in PubMed
- Nachega JB, Nsanzimana S, Rawat A, Wilson LA, Rosenthal PJ, Siedner MJ, Varma JK, Kilmarx PH, Mutesa L, Tanner M, Binagwaho A, Forrest J, Mbala-Kingebeni P, Muyembe-Tamfum JJ, Ntoumi F, Zumla A, de Oliveira T, Mills EJ. Advancing detection and response capacities for emerging and re-emerging pathogens in Africa. Lancet Infect Dis. 2022 Dec 20. View in PubMed
- Nachega JB, Sam-Agudu NA, Machekano RN, Rosenthal PJ, Schell S, de Waard L, Bekker A, Gachuno OW, Kinuthia J, Mwongeli N, Budhram S, Vannevel V, Somapillay P, Prozesky HW, Taljaard J, Parker A, Agyare E, Opoku AB, Makarfi AU, Abdullahi AM, Adirieje C, Ishoso DK, Pipo MT, Tshilanda MB, Bongo-Pasi Nswe C, Ditekemena J, Sigwadhi LN, Nyasulu PS, Hermans MP, Sekikubo M, Musoke P, Nsereko C, Agbeno EK, Yeboah MY, Umar LW, Ntakwinja M, Mukwege DM, Birindwa EK, Mushamuka SZ, Smith ER, Mills EJ, Otshudiema JO, Mbala-Kingebeni P, Tamfum JM, Zumla A, Tsegaye A, Mteta A, Sewankambo NK, Suleman F, Adejumo P, Anderson JR, Noormahomed EV, Deckelbaum RJ, Stringer JSA, Mukalay A, Taha TE, Fowler MG, Wasserheit JN, Masekela R, Mellors JW, Siedner MJ, Myer L, Kengne AP, Yotebieng M, Mofenson LM, Langenegger E, AFREhealth Research Collaboration on COVID-19 and Pregnancy. Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Pregnancy in Sub-Saharan Africa: A 6-Country Retrospective Cohort Analysis. Clin Infect Dis. 2022 11 30; 75(11):1950-1961. View in PubMed
- Felzen A, van Wessel DBE, Gonzales E, Thompson RJ, Jankowska I, Shneider BL, Sokal E, Grammatikopoulos T, Kadaristiana A, Jacquemin E, Spraul A, Lipinski P, Czubkowski P, Rock N, Shagrani M, Broering D, Nicastro E, Kelly D, Nebbia G, Arnell H, Fischler B, Hulscher JBF, Serranti D, Arikan C, Polat E, Debray D, Lacaille F, Goncalves C, Hierro L, Mu?oz Bartolo G, Mozer-Glassberg Y, Azaz A, Brecelj J, Dezsofi A, Calvo PL, Grabhorn E, Hartleif S, van der Woerd WJ, Kamath BM, Wang JS, Li L, Durmaz ?, Kerkar N, J?rgensen MH, Fischer R, Jimenez-Rivera C, Alam S, Cananzi M, Laverdure N, Ferreira CT, Guerrero FO, Wang H, Sency V, Kim KM, Chen HL, de Carvalho E, Fabre A, Bernabeu JQ, Zellos A, Alonso EM, Sokol RJ, Suchy FJ, Loomes KM, McKiernan PJ, Rosenthal P, Turmelle Y, Horslen S, Schwarz K, Bezerra JA, Wang K, Hansen BE, Verkade HJ, NAtural course and Prognosis of PFIC and Effect of biliary Diversion (NAPPED) Consortium. Genotype-phenotype relationships of truncating mutations, p.E297G and p.D482G in bile salt export pump deficiency. JHEP Rep. 2023 Feb; 5(2):100626. View in PubMed
- View All Publications
In the News
- UCSF Transplant Surgery - December 28, 2012Alfonso Garcia and his parents pose with the UCSF medical team that cared for him during his 2010 life-saving liver transplant. From left: mother Marta Garcia; Emily Perito, MD; nurse practitioner Susan Diaz, MSN; Garcia; Philip Rosenthal, MD; and father Oscar Garcia. Alfonso Garcia still carries around a baseball cap that belonged to a 22-year-old man who passed away in 2010 having never met him. But the cap is just a small token of an even bigger reminder that the 18-year-old college [...]
- UCSF Transplant Surgery - October 01, 2001UCSF Medical Center staff performed the biopsy and told us the next day that William had a condition called biliary atresia, which is the closure or absence of some or all of the major bile ducts. That evening William had surgery to assess the damage to his liver and to open bile ducts. Later, during clinic visits with Dr. Phil Rosenthal (pictured left) and pediatric nurse practitioner and Liver Transplant Coordinator Chris Mudge, we learned about a relatively new procedure call a living [...]
