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Jennifer C. Lai, M.D., M.B.A.

Jennifer C. Lai, M.D., M.B.A.

Assistant Professor of Medicine
General Hepatology and Liver Transplantation
Department of Medicine

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Stanford University, BS, Biology, 1996-2000

Tufts University School of Medicine, MD, MBA, 2001-2005

  • New York Presbyterian Hospital-Columbia, Intern, Internal Medicine, 2005-2006
  • New York Presbyterian Hospital-Columbia, Resident, Internal Medicine, 2006-2008
  • University of California, San Francisco, Fellow, Gastroenterology, 2008-2011
  • University of California, San Francisco, Fellow, Transplant Hepatology, 2011-2012
  • University of California, San Francisco, Advanced Training in Clinical Research, 2009-2010
  • American Board of Internal Medicine
  • American Board of Internal Medicine - Gastroenterology
  • UCSF Liver Center
  • Hepatitis C virus (HCV)
  • Impact of function status in patients on the liver-transplant waiting list
  • Patterns of donor liver allocation and liver transplant outcomes

Dr. Jennifer C. Lai is a general and transplant hepatologist, specializing in treating patients with chronic viral hepatitis (both B and C), autoimmune disorders, and those with end-stage liver disease needing liver transplantation. 

After earning her undergraduate degree from Stanford University and combined MD/MBA degrees from Tufts University, she completed residency at the New York Presbyterian Hospital-Columbia and gastroenterology and advanced/transplant hepatology fellowships at UCSF. She is a member of the American Association for the Study of Liver Diseases, American Society of Transplantation, American Gastroenterological Association, and American College of Gastroenterology. She has been recognized as a Fellow of the American College of Physicians (FACP). Dr. Lai is board certified in Internal Medicine and Gastroenterology. 

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  • Young Investigator Award in Clinical Science, American Gastroenterological Association (AGA), 2020
  • Floyd Rector Internal Medicine Research Mentoring Award, UCSF, 2019
  • Fellow, American Society of Transplantation, 2017
  • AST/Novartis Faculty Development Award (grant), American Society of Transplantation, 2016-2017
  • Clinical Science Career Development Award, American Society of Transplantation, 2016
  • New Investigator Award, American Geriatrics Society, 2015
  • Young Investigator Award, International Liver Transplantation Society, 2015
  • Paul B. Beeson Scholar in Aging Research (grant), American Federation for Aging Research, 2014-2019
  • Associate Scholar Genius Award (grant), UCSF Pepper Center, 2014-2015
  • T. Franklin Williams Scholar (grant), Association of Specialty Professors, 2013-2015
  • Pilot/Feasibility Award (grant), UCSF Liver Center, 2013-2014
  • Pilot Award in Aging Research (grant), UCSF Pepper Center, 2013-2014
  • Pilot for Junior Investigator Award (grant), UCSF Resource Allocation Program, 2013-2014
  • Fellow, American College of Physicians, 2012-curr
  • Junior Faculty Career Development Award (grant), American College of Gastroenterology, 2012-2015
  • Transplant Hepatology Fellowship (grant), American Association for the Study of Liver Diseases, 2011-2012
  • Clinical Research Award (grant), American College of Gastrenterology, 2011-2012
  • Vanguard Award, International Liver Transplantation Society, 2011
  • Sylvia Allison Kaplan Clinical Research Award (grant), Northern California Kaiser Permanente, 2009-2010
  • Alpha Omega Alpha, Tufts University School of Medicine, 2005
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Dr. Lai has engaged in research investigating clinical outcomes in patients with chronic liver disease. Her research focuses on three main areas:

1) Understanding the impact of functional status and physiologic reserve (i.e., frailty) in patients with cirrhosis awaiting liver transplantation (actively enrolling)

2) Evaluating the association between chronic hepatitis C and systemic inflammation with Vitamin D status and bone mineral density (actively enrolling)

3) Characterizing patterns of liver allocation and distribution and their association with liver transplant outcomes (both pre- and post-transplant) on a national level

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  • Predicting post-transplant mortality and global functional health based on pre-transplant functional status in liver transplantation
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    Jun 2018
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    May 2023
    Principal Investigator
  • Development of a laboratory frailty index to improve prediction of mortality in patients with cirrhosis awaiting liver transplantation
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    May 2020
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    Apr 2022
    Principal Investigator
  • Frailty and Functional Status in Older Liver Transplant Patients
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    Sep 2014
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    Apr 2019
    Principal Investigator
  • Global Functional Status in the Older Liver Transplant Candidate
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    Aug 2013
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    Jul 2015
    Principal Investigator
Data provided by UCSF Profiles, powered by CTSI
MOST RECENT PUBLICATIONS FROM A TOTAL OF 130
Data provided by UCSF Profiles, powered by CTSI
  1. Bajaj JS, Reddy KR, O'Leary JG, Vargas HE, Lai JC, Kamath PS, Tandon P, Wong F, Subramanian RM, Thuluvath P, Fagan A, White MB, Gavis EA, Sehrawat T, Rodriguez RR, Thacker LR, Sikaroodi M, Garcia-Tsao G, Gillevet PM. Serum Levels of Metabolites Produced by Intestinal Microbes and Lipid Moieties Independently Associated With Acute on Chronic Liver Failure and Death in Patients With Cirrhosis. Gastroenterology. 2020 Jul 17. View in PubMed
  2. Wadhwani SI, Brokamp C, Rasnick E, Bucuvalas JC, Lai JC, Beck AF. Neighborhood socioeconomic deprivation, racial segregation, and organ donation across 5 states. Am J Transplant. 2020 Jul 12. View in PubMed
  3. Fozouni L, Lai JC. Frailty as an Immune-Mediated Condition That Leads to an Increased Risk of Acute Cellular Rejection in Liver Transplant Recipients. Clin Liver Dis (Hoboken). 2020 Jun; 15(6):243-245. View in PubMed
  4. Wong RJ, Mohamad Y, Srisengfa YT, Kent DS, Seetharaman S, Shah RJ, Lai JC. Psychological contributors to the frail phenotype: the association between resilience and frailty in patients with cirrhosis. Am J Transplant. 2020 Jun 10. View in PubMed
  5. Wang CW, Lebsack A, Sudore RL, Lai JC. Low Rates of Advance Care Planning (ACP) Discussions Despite Readiness to Engage in ACP Among Liver Transplant Candidates. Dig Dis Sci. 2020 Jun 04. View in PubMed
  6. View All Publications

 

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