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Claus U. Niemann, M.D.

Claus U. Niemann, M.D.

Professor of Anesthesia and Surgery

Department of Anesthesia & Perioperative Care
Department of Surgery

Co-Director, Ischemic Organ Injury Lab

Contact Information

University of California, San Francisco
500 Parnassus MUE 4th Floor
Box 0648
San Francisco, Ca 94143-0648
Tel: 415-502-2162
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  • 1986-93, Ludwig-Maximilians University, Munich, Germany, M.D.
  • 1993-94  Intern ;  City Hospital St. Georg,, University of Hamburg, Germany and Klinikum Grosshadern, Ludwig-Maximilians University, Munich, Germany
  • 1996-99, University of California, San Francisco, Resident, Anesthesia
  • 1999-01, University of California, San Francisco, Fellow, Liver Transplant Research
  • 1994-96, Department of Anesthesiology, Northwestern University, Chicago, Illinois, Fellow, Postdoctoral Research
  • American Board of Anesthesiology
  • Department of Anesthesia and Perioperative Care
  • Department of Surgery, Division of Transplantation
  • UCSF Liver Center
  • Kidney Transplantation
  • Liver Transplantation
  • Pancreas Transplantation
  • View Research Profile at UCSF Clinical & Translational Science Institute

  • Inflammatory response to injuryIschemia reperfusion injury
  • Intensive Insulin Therapy in Deceased Donors-to improve renal allograft function and transplanted allograft outcomes
  • Liver transplantation
  • Metabolomics
  • Organ donation
  • Renal and hepatic injury during surgery

My group is interested in identifying why obese individuals are at greater risk of liver injury in the setting of trauma or surgery. My long-term goal is to understand the relationship between metabolic and immunologic processes in the liver. One potential link between these underlying mechanisms could be the peptide leptin, which can profoundly modify inflammatory and metabolic pathways. The goal of this research effort is to improve understanding of the impact of leptin on acute inflammatory cascade and metabolic response during hepatic ischemia-reperfusion. This will benefit patients by improving risk-stratification of candidates for hepatic surgery and possibly lead to preventive therapies for ischemia-reperfusion injury. 

Publications provided by UCSF Profiles, powered by CTSI.
  1. Niemann CU. Bacchus Listed for a Liver Transplant: Comment. Anesthesiology. 2020 03 24. View in PubMed
  2. Niemann CU, Biancofiore G. Transplant anesthesia and critical care: Current research and possible future developments. Best Pract Res Clin Anaesthesiol. 2020 Mar; 34(1):1-2. View in PubMed
  3. Patel MS, Mohebali J, Coe TM, Sally M, Groat T, Niemann CU, Malinoski DJ, Vagefi PA. The role of deceased donor liver biopsy: An analysis of 5449 liver transplant recipients. Clin Transplant. 2020 Feb 18; e13835. View in PubMed
  4. Malinoski D, Patel MS, Axelrod DA, Broglio K, Lewis RJ, Groat T, Niemann CU. Therapeutic Hypothermia in Organ Donors: Follow-up and Safety Analysis. Transplantation. 2019 Nov; 103(11):e365-e368. View in PubMed
  5. Axelrod DA, Malinoski D, Patel MS, Broglio K, Lewis R, Groat T, Lentine KL, Schnitzler M, Niemann CU. Modeling the economic benefit of targeted mild hypothermia in deceased donor kidney transplantation. Clin Transplant. 2019 07; 33(7):e13626. View in PubMed
  6. View All Publications


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